Cardiovascular Applications

SurModics works with the world’s leading cardiovascular disease companies to enhance their products, as well as create new ones.  Our experience includes integration of our drug delivery polymer matrices onto implantable devices, application of hydrophilic coatings onto various delivery and delivery-like systems, and integration of our prohealing coatings on coronary stents.

Key Cardiovascular Disease Capabilities:

  • Durable and biodegradable polymer-based drug coatings for delivery of
    • Various drugs for drug eluting stents
    • Steroids for leads, implants
    • Variety of small and large molecule drugs
  • Surface Modification Coatings
    • Advanced Hydrophilic coatings for delivery systems, catheters, guidewires, CRM leads
    • Hemocompatible coatings, employing heparin and other agents
    • Prohealing coatings for rapid endothelialization of stents and other implants

 

Project Examples

  • Drug Delivery: Cordis Corporation, Johnson & Johnson company
    • Product: Cypher® Sirolimus-eluting Coronary Stent
    • Collaboration on drug eluting stent coating
    • Integration of our Bravo™ Drug Delivery Polymer Matrix as a key component for drug delivery
  • Drug Delivery: CardioMind
    • Product:  Ultra low profile stent system for the treatment of coronary and peripheral artery disease
    • Collaboration on drug eluting stent coating
    • SynBiosys Biodegradable Drug Delivery System provides desirable drug elution, degradation, and adhesion properties with the CardioMind stent
  • Prohealing: Paragon
    • Product: PROTEX TM  cobalt alloy stent system
    • Collaboration on prohealing coating applied to bare metal stent
    • FINALE TM prohealing coating to accelerate the natural healing response
  • Advanced Hydrophilic Coatings: St. Jude
    • Product: Cardiac Rhythm Management leads
    • Use of SurModics’ Advanced Hydrophilic Coating technology
  • Advanced Hydrophilic Coatings: Abbott
    • Product: Vascular Closure Device
    • Use of SurModics’ Advanced Hydrophilic Coating technology