In Vitro Technologies
SurModics serves the in vitro diagnostics, biopharmaceutical and research markets with a variety of product offerings, including:
- Protein stabilization reagents
- Colorimetric and chemiluminescent substrates
- Immunoreagents (secondary antibodies, blockers, diluents)
- Autoimmune antigens
- Synthetic ECM (extracellular matrix) cell culture surfaces
- Activated slides for DNA immobilization
Protein Stabilization Reagents
Protein stabilizers are available for immunoassays in the dry state, HRP and AP conjugates in solution, and microarray proteins including those that are immobilized to beads in suspension or stored in the dry state. These products are ready-to-use, eliminating the time and cost of producing stabilization and blocking reagents in-house. BSA-free versions are available.
BioFX® Substrates
With the August 2007 acquisition of BioFX Laboratories, SurModics now offers colorimetric and chemiluminescent substrates for assay detection. These BioFX substrates have an established reputation for high-quality and performance. SurModics also offers secondary reagents including antibodies, blockers, buffers, diluents, and stains.
Autoimmune Antigens
SurModics is the exclusive North American distributor of DIARECT AG’s line of recombinant autoimmune antigens. Because of the lack of high-quality antigens from natural sources, DIARECT produces these proteins and other components using biotechnological methods. DIARECT has strong capabilities in the bacilovirus/Sf9 expression system for autoimmune antigens as well as E. coli systems for particular expression tasks.
SurModics® Synthetic ECM
SurModics® Synthetic ECM with Ultra-Web™ technology is a nanofibrillar cell culture surface that provides a biomimetic environment for more consistent and reproducible in vivo-like cell phenotypes, leading to more biologically accurate results. The Ultra-Web technology involves electrospinning various polymers to produce a nanofiber material that is a defined and reproducible cell culture surface. Modification of the nanofibers with specific SurModics surface chemistries and functional groups can further enhance the desired cell matrix interactions.
CodeLink® Activated Slides
CodeLink Activated Slides are designed to covalently immobilize amine-modified DNA for microarrays. They are easy to use and are compatible with most available arraying and scanning instruments. The slides are currently offered by GE Healthcare in both standard and high density versions.